HIV-1, Human Protein Interaction Database
What you can do:
Search for documented interaction of human immunodeficiency virus type 1 (HIV-1) proteins with those of the host cell.
Highlights:
- The 'Human Immunodeficiency Virus Type 1 (HIV-1), Human Protein Interaction Database', available through the National Library of Medicine, was created to catalog all interactions between HIV-1 and human proteins published in the peer-reviewed literature.
- The database serves the scientific community exploring the discovery of novel HIV vaccine candidates and therapeutic targets.
- To facilitate this discovery approach, the following information for each HIV-1 human protein interaction is provided and can be retrieved without restriction by web-based downloads and ftp protocols: Reference Sequence (RefSeq) protein accession numbers, Entrez Gene identification numbers, brief descriptions of the interactions, searchable keywords for interactions and PubMed identification numbers (PMIDs) of journal articles describing the interactions.
- 2589 unique HIV-1 to human protein interactions and 5135 brief descriptions of the interactions, with a total of 14,312 PMID references to the original articles reporting the interactions, are stored in this growing database.
- All protein-protein interactions documented in the database are integrated into Entrez Gene records and listed in the 'HIV-1 protein interactions' section of Entrez Gene reports.
- The database is tightly linked to other databases through Entrez Gene, enabling users to search for an abundance of information related to HIV pathogenesis and replication.
Keywords:
- HIV-1
- human immunodeficiency virus type 1
- HIV
- HIV-1 proteins
- AIDS
- protein-protein interactions
Literature & Tutorials:
This record last updated: 04-15-2009