HRTBLDb -- Hormone Receptor Target Binding Loci Database
What you can do:
Find information about hormone protein interactions.
Highlights:
- The Hormone Receptor Target Binding Loci is a data management system organize data about the estrogen receptor (ER), the androgen receptor (AR) and glucocorticoid receptor (GR).
- This database contains hormone receptor binding regions (binding loci) from in vivo ChIP-based high-throughput experiments as well as in silico, computationally predicted, binding motifs and cis-regulatory modules for the co-occurring transcription factor binding motifs, which are within a binding locus.
- It also contains individual binding sites whose regulatory action has been verified by in vitro experiments.
- The current version contains 44 673 binding elements with 114 hormone response elements which are verified by in vitro experiments; 75 binding motifs which occur with a hormone response element and whose co-regulatory action is verified by in vitro experiments; 18 472 binding loci from in vivo experiments; and 26 012 computationally predicted binding motifs.
Keywords:
- hormone
- hormone receptor
- estrogen receptor
- androgen receptor
- glucocorticoid receptor
- ChIP
- chromatin immunoprecipitate
- hormone receptor transcriptional regulation
Literature & Tutorials:
This record last updated: 12-1-09