TRIP database -- TRansient receptor potential channel-Interacting Protein Database
What you can do:
Find information about protein-protein interactions of mammalian TRP channels.
Highlights:
- To facilitate the understanding of the molecular network by which TRP channels are associated with biological and disease processes, the TRIP (TRansient receptor potential channel-Interacting Protein) Database was developed.
- It is a manually curated database that aims to offer comprehensive information on protein-protein interactions (PPIs) of mammalian TRP channels.
- It was created by systematically curating 277 peer-reviewed literature; the current version documents 490 PPI pairs, 28 TRP channels and 297 cellular proteins.
- It provides a detailed summary of PPI data that fit into four categories: screening, validation, characterization and functional consequence.
- Users can find in-depth information specified in the literature on relevant analytical methods and experimental resources, such as gene constructs and cell/tissue types.
Keywords:
- TRP channels
- transient receptor potential channel
- Ca(2+)-permeable cation channels
- PPI
- protein-protein interaction
Literature & Tutorials:
This record last updated: 06-14-2011