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At the University of Pittsburgh, literature searches for the “3R’s” are required for Institutional Animal Care and Use Committee (IACUC) protocols using warm-blooded species that are classified in the USDA Pain Classifications D or E (other than birds, mice of the genus Mus, and rats of the genus Rattus).
Researchers needing assistance to meet this requirement can consult with a librarian who can conduct the searches, offer keyword suggestions, or provide training on a database.