BOMP -- A Program to Predict Integral xdf-barrel Outer Membrane Proteins Encoded within Genomes of Gram-negative Bacteria

What you can do:
Predict whether or not a polypeptide sequence from a Gram-negative bacterium is an integral xdf-barrel outer membrane protein.
Highlights:
  • BOMP is based on two separate components to recognize integral xdf-barrel proteins. The first component is a C-terminal pattern typical of many integral xdf-barrel proteins. The second component calculates an integral xdf-barrel score of the sequence based on the extent to which the sequence contains stretches of amino acids typical of transmembrane xdf-strands.
  • The precision of the predictions was found to be 80% with a recall of 88% when tested on the proteins with SwissProt annotated subcellular localization in Escherichia coli K12 (788 sequences) and Salmonella typhimurium (366 sequences).
Keywords:
  • integral xdf-barrel outer membrane proteins
  • Gram-negative bacterial proteins
  • membrane proteins
  • integral xdf-barrel proteins
  • protein structure prediction
Literature & Tutorials:
PubMed Link: BOMP
This record last updated: 05-11-2005
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