Predict whether or not a polypeptide sequence from a Gram-negative bacterium is an integral xdf-barrel outer membrane protein.
Highlights:
BOMP is based on two separate components to recognize integral xdf-barrel proteins. The first component is a C-terminal pattern typical of many integral xdf-barrel proteins. The second component calculates an integral xdf-barrel score of the sequence based on the extent to which the sequence contains stretches of amino acids typical of transmembrane xdf-strands.
The precision of the predictions was found to be 80% with a recall of 88% when tested on the proteins with SwissProt annotated subcellular localization in Escherichia coli K12 (788 sequences) and Salmonella typhimurium (366 sequences).