Scooby-domain -- prediction of globular domains in protein sequence
What you can do:
Identify globular domains in protein sequences.
Highlights:
- Scooby-domain is a fast and simple method to identify globular domains in protein sequence, based on the observed lengths and hydrophobicities of domains from proteins with known tertiary structure.
- The prediction method successfully identifies sequence regions that will form a globular structure and those that are likely to be unstructured.
- The method does not rely on homology searches and, therefore, can identify previously unknown domains for structural elucidation.
- Scooby-domain is available as a Java applet.
- It may be used to visualize local properties within a protein sequence, such as average hydrophobicity, secondary structure propensity and domain boundaries, as well as being a method for fast domain assignment of large sequence sets.
Keywords:
- protein domain assignment tool
- globular domain prediction tool
- protein structure prediction tool
Literature & Tutorials:
This record last updated: 09-22-2005