Localizome -- a server for identifying transmembrane topologies and TM helices of eukaryotic proteins utilizing domain information

URL:
http://localizome.org/
What you can do:
Predict the transmembrane (TM) helix number and TM topology of a user-supplied eukaryotic protein.
Highlights:
  • The Localizome server predicts the transmembrane helix number and topology of a eukaryotic protein, using hmmpfam to detect the presence of Pfam domains and a prediction algorithm, Phobius, to predict the TM helices.
  • The results are checked against LocaloDom, a curated protein domain database that contains TM topologies and TM helix numbers of known protein domains.
  • With a graphical representation of TM topology and TM helix positions with the domain units, the Localizome server is a highly accurate and comprehensive information source for subcellular localization for soluble proteins as well as membrane proteins.
Keywords:
  • transmembrane protein analysis tool
  • transmembrane protein structure prediction tool
  • transmembrane protein topology prediction tool
  • transmembrane protein helix prediction tool
  • soluble proteins
  • protein subcellular localization
Literature & Tutorials:
PubMed Link: Localizome -- a server for identifying transmembrane topologies and TM helices of eukaryotic proteins utilizing domain information
This record last updated: 07-17-2006
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