StSNP -- Structure SNP

What you can do:
A web server for mapping and modeling nsSNPs on protein structures with linkage to metabolic pathways.
Highlights:
  • The data from NCBI's SNP database (dbSNP), gene and protein databases from Entrez, protein structures from the PDB and pathway information from KEGG have all been cross referenced into the StSNP web server, in an effort to provide combined integrated, reports about nsSNPs.
  • StSNP provides 'on the fly' comparative modeling of nsSNPs with links to metabolic pathway information, along with real-time visual comparative analysis of the modeled structures using the Friend software application.
  • The use of metabolic pathways in StSNP allows a researcher to examine possible disease-related pathways associated with a particular nsSNP(s), and link the diseases with the current available molecular structure data.
Keywords:
  • Chromosome Mapping
  • Open Reading Frames
  • Single Nucleotide Polymorphism
  • Protein Interaction Mapping
  • Sequence Alignment
  • Sequence Analysis
  • SNP
  • non-synonymous
  • nsSNP
  • metabolic pathways
  • protein structure
This record last updated: 04-21-2014

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