SAHG -- Structural Atlas of the Human Genome

What you can do:
Find information about human protein structures.
Highlights:
  • SAHG is a special protein-structure-prediction pipeline.
  • With the pipeline, human proteins were examined by local alignment methods (BLAST, PSI-BLAST and Smith-Waterman profile-profile alignment), global-local alignment methods (FORTE) and prediction tools for ID regions (POODLE-S) and homology modeling (MODELLER).
  • Conformational changes of protein models upon ligand-binding were predicted by simultaneous modeling using templates of apo and holo forms.
  • When there were no suitable templates for holo forms and the apo models were accurate, we prepared holo models using prediction methods for ligand-binding (eF-seek) and conformational change (the elastic network model and the linear response theory).
  • Models are displayed as animated images.
  • As of July 2010, SAHG contains 42,581 protein-domain models in approximately 24,900 unique human protein sequences from the RefSeq database.
  • Annotation of models with functional information and links to other databases such as EzCatDB, InterPro or HPRD are also provided to facilitate understanding the protein structure-function relationships.
Keywords:
  • protein structure
  • human protein
This record last updated: 06-14-2011
Report a missing or misdirected URL.

The Health Sciences Library System supports the Health Sciences at the University of Pittsburgh.

© 1996 - 2023 Health Sciences Library System, University of Pittsburgh. All rights reserved.