I-TASSER: Protein Structure & Function Predictions
What you can do:
I-TASSER (Iterative Threading ASSEmbly Refinement) is an internet service for protein structure and function predictions.
Highlights:
- Allows academic users to automatically generate high-quality predictions of 3D structure and biological function of protein molecules from their amino acid sequences.
- The output of the I-TASSER server include:
- Up to five full-length atomic models (ranked based on cluster density)
- Estimated accuracy of the predicted models (including a confidence score of all models, and predicted TM-score and RMSD for the first model)
- GIF images of the predicted models
- Predicted secondary structures
- Predicted solvent accessibility
- Top 10 threading alignment from LOMETS
- Top 10 proteins in PDB which are structurally closest to the predicted models
- Predicted Enzyme Classification and the confidence score
- Predicted GO terms and the confidence score
- Predicted ligand-binding sites and the confidence score
- An image of the predicted ligand-binding sites
Keywords:
- protein structure prediction
- 3D structure
- protein function
- threading
- contact prediction
- free modeling
Literature & Tutorials:
This record last updated: 11-03-2015