TargetRNA -- a tool for predicting targets of small RNA action in bacteria
What you can do:
Identify targets of small (non-coding) RNA action.
Highlights:
- TargetRNA takes as input a genomic sequence that may correspond to an sRNA gene.
- TargetRNA then uses a dynamic programming algorithm to search each annotated message in a specified genome for mRNAs that evince basepair-binding potential to the input sRNA sequence.
- Based on the calculated basepair-binding potential of each message with the given sRNA regulator, TargetRNA outputs a ranked list of candidate mRNA targets along with the predicted basepairing interaction of each target to the sRNA.
- The predictive performance of TargetRNA has been validated experimentally in several bacterial organisms.
Keywords:
- sRNA
- small RNA
- bacteria RNA
Literature & Tutorials:
This record last updated: 07-21-2008